D4317

3,5-Diiodothyropropionic acid

• Synonym(s): DITPA
• Empirical Formula (Hill Notation): C₁₅H₁₂I₂O₄
• CAS Number: 1158-10-7
• Molecular Weight: 510.06
• UNSPSC Code: 12352200
• PubChem Substance ID: 24893861
• MDL number: MFCD00045945

Properties

• storage temp.: 2-8°C
• SMILES string: OC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1

Description

Biochem/physiol Actions

DITPA, an analog of L-thyroxine, has inotropic but not chronotropic effects on heart muscle. It also stimulates myocardial angiogenesis after infarction by interaction with integrin αvཪ3 at the cell surface.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves