The solution stability of this product has not been determined. It is recommended to prepare solutions fresh before use.
C0158
L-Carnitine inner salt
≥98%
Synonym(s):
(−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin BT
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1 G
€39.80
5 G
€72.60
25 G
€331.00
100 G
€1,040.00
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1 G
€39.80
5 G
€72.60
25 G
€331.00
100 G
€1,040.00
About This Item
Linear Formula:
(CH3)3N+CH2CH(OH)CH2COO-
CAS Number:
Molecular Weight:
161.20
Beilstein:
4292315
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.79
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Product Name
L-Carnitine inner salt, synthetic, ≥98%
biological source
synthetic
Quality Level
Assay
≥98%
form
powder
color
white
mp
197-212 °C (lit.)
application(s)
cell analysis
detection
SMILES string
C[N+](C)(C)C[C@H](O)CC([O-])=O
InChI
1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChI key
PHIQHXFUZVPYII-ZCFIWIBFSA-N
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Application
L-Carnitine inner salt has been used as a component of an assay medium for Seahorse XF mitochondrial stress assay.[1] It has also been orally administered to tumor-bearing mice, in order to study its effect on the regulation of peroxisome proliferator-activated receptor and thereby to analyse liver inflammatory response.[2]
Biochem/physiol Actions
Carnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment.[3] In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branched chain amino acids.[4]
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Obesity and dyslipidaemia are metabolic defects resulting from impaired lipid metabolism. These impairments are associated with the development of cardiovascular disease and non-alcoholic fatty liver disease. Correcting the defects in lipid metabolism may attenuate obesity and dyslipidaemia, and reduce cardiovascular
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N A Oey et al.
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Carnitine plays an indispensable role in fatty acid oxidation. Previous studies revealed that fetal carnitine is derived from the mother via transplacental transfer. Recent studies demonstrated the presence and importance of an active fatty acid oxidation system in the human
Sandra Wächter et al.
Clinica chimica acta; international journal of clinical chemistry, 318(1-2), 51-61 (2002-03-07)
Long-term administration of high oral doses of L-carnitine on the skeletal muscle composition and the physical performance has not been studied in humans. Eight healthy male adults were treated with 2 x 2 g of L-carnitine per day for 3
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