A9546
2-Amino-6-methylmercaptopurine
≥95%
Synonym(s):
2-Amino-6-methylthiopurine
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About This Item
Empirical Formula (Hill Notation):
C6H7N5S
CAS Number:
Molecular Weight:
181.22
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
214-833-4
MDL number:
Assay:
≥95%
Form:
solid
Quality Segment
assay
≥95%
form
solid
SMILES string
[H]n1cnc2c(SC)nc(N)nc12
InChI
1S/C6H7N5S/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)
InChI key
YEGKYFQLKYGHAR-UHFFFAOYSA-N
Application
2-Amino-6-methylmercaptopurine is a 2-amino-6-alkyldithiopurine that has been used with other 6-position carbon analogues to study brain specific diazepam binding.
2-Amino-6-methylmercaptopurine (6-MTG) has been used as a supplement in Dulbecco′s modified Eagles medium (DMEM) medium for the selection of gpt-expressing recombinant virus mCMVhMIEPE-gpt.lacZ (cytomegalovirus major immediate-early promotor-enhancer complex-gpt.lacz). It has also been used as a standard in high performance liquid chromatography (HPLC) to assess the activity of thiopurine methyltransferase (TPMT) enzyme.
Biochem/physiol Actions
2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme.
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This Item | |||
|---|---|---|---|
| description ≥95% | description ≥95%, crystalline | description 98% | description Pharmaceutical Secondary Standard; Certified Reference Material |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 300 |
| assay ≥95% | assay ≥95% | assay 98% | assay - |
| form solid | form crystalline | form powder | form - |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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