A4326
Arylamine acetyltransferase from pigeon liver
lyophilized powder, ~0.5 units/mg protein
Synonym(s):
NAT
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About This Item
biological source
pigeon liver
form
lyophilized powder
specific activity
~0.5 units/mg protein
composition
Protein, ~10% biuret
shipped in
dry ice
storage temp.
−20°C
Unit Definition
One unit will acetylate 1.0 nanomole of p-nitroaniline per min at pH 8.0 at 25 °C.
Physical form
Contains sucrose as a stabilizer.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Journal of toxicology and environmental health. Part A, 75(19-20), 1216-1225 (2012-09-22)
Long-term follow-ups on bladder cancer patients from highly industrialized areas are rare. Therefore, we present a follow-up of bladder cancer patients from the greater area Lutherstadt Wittenberg, a center of the chemical industry of the former German Democratic Republic. Relapse-free
Przeglad lekarski, 69(3), 120-124 (2012-07-07)
The etiology of dermatological diseases is still unknown. Involvement of genetic and environmental factors in the pathogenesis of dermatological diseases has contributed to a number of studies whose aim is to elucidate the way in which xenobiotics exert effects on
Advances in pharmacology (San Diego, Calif.), 63, 169-205 (2012-07-11)
Arylamine N-acetyltransferases (NATs) are defined as xenobiotic metabolizing enzymes, adding an acetyl group from acetyl coenzyme A (CoA) to arylamines and arylhydrazines. NATs are found in organisms from bacteria and fungi to vertebrates. Several isoenzymes, often polymorphic, may be present
Clinica chimica acta; international journal of clinical chemistry, 415, 215-219 (2012-10-27)
The relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver biomarkers was investigated in individuals under anti-tuberculosis drug therapy. Tuberculosis outpatients (18-70 y) with (n=59) and without (n=40) mild increase of liver enzymes (MILE) at two-month treatment
Expert opinion on drug metabolism & toxicology, 8(12), 1521-1530 (2012-09-25)
The quest for a biomarker that would reliably identify patients at risk of developing acute drug-induced liver injury (DILI) to a specific agent or class of agents before it occurs, has been underway for years. Historical host factors for DILI
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