82934
7-Hydroxycitronellal
Odorant used in allergy studies
Synonym(s):
7-Hydroxy-3,7-dimethyloctanal, Citronellal hydrate
Sign Into View Organizational & Contract Pricing
All Photos(1)
Select a Size
Change View
25 G
€65.90
About This Item
Empirical Formula (Hill Notation):
C10H20O2
CAS Number:
Molecular Weight:
172.26
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.52
Recommended Products
grade
for molecular biology
Quality Level
Assay
≥95.0% (GC)
form
powder
density
0.92 g/mL at 20 °C (lit.)
storage temp.
room temp
SMILES string
[H]C(CC(C)CCCC(O)(C)C)=O
InChI
1S/C10H20O2/c1-9(6-8-11)5-4-7-10(2,3)12/h8-9,12H,4-7H2,1-3H3
InChI key
WPFVBOQKRVRMJB-UHFFFAOYSA-N
General description
7-Hydroxycitronellal is fragrant sensitizer added frequently to deodorants and perfumes. It is one of the allergens responsible for axillary dermatitis.[1]
Application
Suitable for
- contact sensitization studies to identify allergens present in cosmetic preparations
- elucidation of molecular pathways related to allergic reactions
- analytical standard
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Nadège Ade et al.
Toxicological sciences : an official journal of the Society of Toxicology, 107(2), 451-460 (2008-11-27)
Electrophilicity is one of the most common features of skin contact sensitizers and is necessary for protein haptenation. The Keap1 (Kelch-like ECH-associated protein 1)/Nrf2 -signaling pathway is dedicated to the detection of electrophilic stress in cells leading to the upregulation
M Cluzel-Tailhardat et al.
Toxicology letters, 174(1-3), 98-109 (2007-10-16)
A critical step in the induction of allergic contact dermatitis is the interaction of haptens with immature dendritic cells (iDC) leading to their activation. Therefore iDC appear as suitable targets for the evaluation of the sensitizing properties of haptens with
B Kreilgård et al.
Journal of the American Academy of Dermatology, 21(4 Pt 2), 836-838 (1989-10-01)
The choice of vehicle for patch test materials is important for the bioavailability and stability of the allergens. Examples are given from the standardization of the TRUE Test and include caine mix, Kathon CG, and fragrance mix.
R A Ford et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(11-12), 921-926 (1988-11-01)
Hydroxycitronellal, an important ingredient in fragrances, was studied for its sensitizing potential in human skin. Fifteen human maximization tests were conducted with hydroxycitronellal obtained from four different sources at induction concentrations from 5 to 12%. No reactions were induced at
H Wahlkvist et al.
Contact dermatitis, 41(4), 198-206 (1999-10-09)
A multi-dose-response induction protocol for the guinea pig maximization test (GPMT), including a statistical computer program, has earlier been developed to improve the power of predictive tests for identification of contact allergens. This dose-response protocol, with 2 modifications (i.e., increased
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
