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22048

Sigma-Aldrich

κ-Carrageenan

sulfated plant polysaccharide

Synonym(s):

Vegetable gelatin

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25 G
€48.30
100 G
€152.00

€48.30


Estimated to ship on30 March 2025


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25 G
€48.30
100 G
€152.00

About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

€48.30


Estimated to ship on30 March 2025


Request a Bulk Order

biological source

plant

Quality Level

form

powder

color

white to off-white

viscosity

5-25 mPa.s, 0.3 % in H2O(25 °C)

solubility

H2O: soluble 5 mg/mL (hot)

SMILES string

[S](=O)(=O)([O-])O[C@H]1[C@H](O[C@H]([C@@H]([C@H]1O[C@H]4O[C@H]5[C@@H]([C@H](OC5)[C@H]4O)O[C@@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O[S](=O)(=O)[O-])CO)O)O[C@@H]2[C@@H]3OC[C@H]2O[C@@H]([C@@H]3O)O)CO

InChI

1S/C24H38O25S2/c25-1-5-14(48-50(33,34)35)9(27)10(28)22(42-5)45-16-8-4-40-19(16)12(30)23(44-8)47-20-13(31)24(43-6(2-26)17(20)49-51(36,37)38)46-15-7-3-39-18(15)11(29)21(32)41-7/h5-32H,1-4H2,(H,33,34,35)(H,36,37,38)/p-2/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14+,15+,16+,17+,18-,19-,20-,21+,22+,23-,24+/m1/s1

InChI key

ZNOZWUKQPJXOIG-XSBHQQIPSA-L

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General description

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.
insoluble in hot concentrated salt solutions

Application

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
May be used in immobilization of microbial cells based on the growth of cell in gel[1][2]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A L Ellis et al.
Journal of colloid and interface science, 538, 165-173 (2018-12-05)
Polysaccharides such as kappa carrageenan are often utilised in fat replacement techniques in the food industry. However, the structural role they can provide within a product is limited by their hydrophilic nature. Hydrophilic particles can be surface-activated by hydrophobic modification
Immobilization of cells in carrageenan.
I Chibata et al.
Methods in enzymology, 135, 189-198 (1987-01-01)
M. Wada et al.
Europ. J. Appl. Microbiol. Biotechnol., 8, 241-241 (1979)
Bakti B Sedayu et al.
Polymers, 12(5) (2020-05-21)
Carrageenans obtained from seaweeds can be processed into films for a range of applications including food packaging. The level of carrageenan refinement during extraction can influence the key properties, with semi-refined carrageenan (SRC) containing more impurities than the more refined
E. Castillo et al.
Applied Biochemistry and Biotechnology, 34-35, 477-477 (1992)

Questions

1–4 of 4 Questions  
  1. What is the average molecular weight for this k-carrageenan?

    1 answer
    1. Unfortunately, the molecular weight is not determined for this product.

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  2. Is this k-carrageenan food grade?

    1 answer
    1. No. This product is intended for research use only. Currently, a food grade κ-Carrageenan product is not available.

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  3. Hi, I'm interested to know how the K-carrageenan is synthesized. Do you use more green production methods such as enzyme assisted extraction, or the more traditional method? Thanks, Rowan

    1 answer
    1. This K-carrageenan product comes from a family of sulphated polysaccharides extracted from certain species of red seaweed. Carrageenan is a cell wall hydrocolloid found in certain species of seaweeds belonging to red algae (class: Rhodophyceae). Carrageenan is extracted with water under neutral or alkaline conditions at elevated temperatures. The exact method of preparation is considered proprietary.

      Helpful?

  4. Can we use this type of carrageenan for inflammatory induction?

    1 answer
    1. Carrageenans are commonly used for inflammation induction. This product (22048) is the kappa isoform. The iota and lambda form are also available - see C1138, 22049, and C1013 for additional options. These products are not tested for use as an inflammation induction agent. The end-user would be responsible for determining suitability.

      Helpful?

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