The purity of this product is not determined. It is tested and sold by activity rather than mass. The lot specific activity is reported in units per mL and can be found in the Certificate of Analysis. Please see the link below for sample Certificate of Analysis:
https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF736758.pdf
02071
Catalase from Corynebacterium glutamicum
solution, deep brown, ≥500000 U/mL
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€ 185,00
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Diagnostics Manufacturers should use alternative grade product: SRE0041
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SMILES string
O(CC)C(=O)c1ccc(cc1)O
InChI
1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
InChI key
NUVBSKCKDOMJSU-UHFFFAOYSA-N
biological source
bacterial (Corynebacterium glutamicum)
form
solution
concentration
≥500000 U/mL
color
deep brown
shipped in
wet ice
storage temp.
2-8°C
Quality Level
1 of 4
This Item | |||
|---|---|---|---|
| form solution | form solution | form ammonium sulfate suspension | form aqueous suspension |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| color deep brown | color dark brown | color - | color - |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
| biological source bacterial (Corynebacterium glutamicum) | biological source bacterial (Micrococcus lysodeikticus) | biological source Aspergillus niger | biological source - |
General description
Catalase is ubiquitously found in animals, plants, fungi, and humans. It is made up of looped polypeptide chains that are arranged as tetramers or dimers and a core, that contains iron or manganese ions. Catalase can be differentiated into two types such as heme-containing (type I), which possesses an iron-porphyrin cofactor and a non-heme-containing (type II), which possesses a dinuclear manganese active site.
Application
Catalase from Corynebacterium glutamicum has been used to identify and characterize purified bacterial peptide (PPBP) produced from Bacillus thuringiensis. It has also been used to study its inhibition by nitric oxide.
Biochem/physiol Actions
Catalase is an antioxidant enzyme that plays a role in alleviating oxidative stress by the removal of hydrogen peroxide to produce oxygen and water. Lower levels of catalase lead to several age-related disorders including hypertension, anemia, vitiligo, Parkinson′s disease, Alzheimer′s disease, schizophrenia, bipolar disorders, diabetes mellitus, and cancer.
Physical form
contains ~30% glycerol, 10% ethanol
Other Notes
1 U corresponds to the amount of enzyme which decomposes 1 μmol H2O2 per minute at pH 7.0 and 25°C
The purity of this product is not determined. It is tested and sold by activity rather than mass.
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
105.8 °F - closed cup
flash_point_c
41 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Nitin Kumar et al.
Science advances, 4(10), eaat7779-eaat7779 (2018-10-20)
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Zh P Kopteva et al.
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Coastal lagoons are constantly subjected to releases of chemical pollutants, and so organisms may be exposed to such toxicants. This study investigated through a multivariate approach the physiological status of bivalve Ruditapes philippinarum, farmed in Sacca di Goro lagoon. Biomarkers
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Early infantile autism is a severe form of childhood psychiatric disease with characteristic symptoms. Hyperserotoninaemia in 43.5%, lactic acidosis 43% and hyperpyruvataemia in 30% were biochemically demonstrated in autistic children. Our earlier results led to the postulation that a dissequilibrium
Danielle de Lima Ávila et al.
Archives of medical research, 44(3), 194-202 (2013-03-26)
It is believed that oxidative stress plays a role in the pathogenesis of diabetes mellitus. Several strategies have been developed with the objective of minimizing diabetic complications. Among these, inhibitors of dipeptidyl peptidase-IV (DPP-IV), which act by blocking degradation of
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