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S6546

Sigma-Aldrich

Sodium chloride solution

Sodium chloride solution

5 M

Synonym(s):

Halite, NaCl, sodium chloride

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About This Item

Linear Formula:
NaCl
CAS Number:
7647-14-5
Molecular Weight:
58.44
Beilstein:
3534976
MDL number:
MFCD00003477
UNSPSC Code:
12352302
PubChem Substance ID:
24899711
NACRES:
NA.25
Pricing and availability is not currently available.

sterility

0.2 μm filtered

Quality Level

200

concentration

5 M

density

1.190 g/cm3

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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General description

Sodium chloride (NaCl), common salt also known as halite, is ubiquitous in occurrence and has many vital applications. It is a white crystalline solid, fairly soluble in water. NaCl is a flavouring agent in the food industry and used for texturing bread and baked foods. NaCl is an essential salt for normal body functions in humans and animals.[1] NaCl is essential for maintaining plasma osmolality and extracellular fluid volume of the body. Excess of NaCl leads to elevated blood pressure which has implications on cardiovascular and renal diseases.[2] NaCl is a basic component in the microbiological medium, specifically for culturing of halophiles.[3] Sterile NaCl is a constituent of eye drop solutions.[4]

Application

Sodium chloride has been used:
  • as a supplement in serum free media for CA3 pyramidal neuron layer preparation[5]
  • in the preparation of oligonucleotides (ODNs) annealing buffer[6]
  • in the preparation of phosphate buffered saline and in phosphatase methylesterase-1 (PME-1) inhibition and counterscreen assay buffers[7]

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000405185
0000406275
0000403956
0000401779
0000391226

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The Actions and Uses of Ophthalmic Drugs: A Textbook for Students and Practitioners (2013)
Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005)
Probe Reports from the NIH Molecular Libraries Program (2010)
Simultaneous reprogramming and gene editing of human fibroblasts
Howden SE, et al.
Nature Protocols, 13(5), 875-875 (2018)
Salt, chlor-alkali and related heavy chemicals
Kent and Riegel's Handbook of Industrial Chemistry and Biotechnology (2010)
View All Related Papers

Protocols

Enzymatic Assay of Sulfatase (EC 3.1.6.1.)

Enzymatic Assay of Sulfatase (EC 3.1.6.1.)

Enzymatic Assay of Collagenase (EC 3.4.24.3) using FALGPA (N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala)

To measure collagenase activity, N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala is used in a continuous spectrophotometric rate determination at 345 nm. Collagenase hydrolyzes collagen peptide bonds.

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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