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A3658

Supelco

N8-Acetylspermidine dihydrochloride

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C9H21N3O · 2HCl
CAS Number:
34450-15-2
Molecular Weight:
260.20
Beilstein:
3698131
MDL number:
MFCD00058263
UNSPSC Code:
41116107
PubChem Substance ID:
329770841
NACRES:
NA.24

grade

analytical standard

technique(s)

mass spectrometry (MS): suitable

format

neat

storage temp.

2-8°C

SMILES string

Cl.Cl.CC(=O)NCCCCNCCCN

InChI

1S/C9H21N3O.2ClH/c1-9(13)12-8-3-2-6-11-7-4-5-10;;/h11H,2-8,10H2,1H3,(H,12,13);2*1H

InChI key

BWGUIRARVGYOIR-UHFFFAOYSA-N

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Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000236746
0000215866
BGBC3323
BGBC3050
BGBC2098

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L Y Wing et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 179-183 (1993-07-01)
Polyamines are polycations in cells and acetylation is the first step in their intracellular metabolism. We investigated the effects of the acetylated polyamines on arterial blood pressure and vascular reactivities in rats. Acetylspermine and acetylspermidine, administered at concentrations ranging from
Measurement of spermidine/spermine N1-acetyltransferase activity.
H M Wallace et al.
Methods in molecular biology (Clifton, N.J.), 79, 59-68 (1998-02-17)
A N Kingsnorth et al.
European journal of cancer & clinical oncology, 21(9), 1057-1062 (1985-09-01)
Normal tissues contain only trace amounts of monoacetylated polyamines. N1-Acetylspermidine is present in high concentrations in mouse liver cells damaged by hepatotoxins and is also found in specialised cells of the hamster epididymis. In the present study human breast cancers
Assay of N8-acetylspermidine deacetylase.
J Blankenship
Methods in molecular biology (Clifton, N.J.), 79, 77-80 (1998-02-17)
B L O'Brien et al.
Digestive diseases and sciences, 40(6), 1269-1274 (1995-06-01)
Urinary N1-acetylspermidine (N1SPD) and N8-acetylspermidine (N8SPD) were measured in 24-hr urine specimens from 42 patients with colon adenocarcinoma and 29 healthy controls to assess their use as markers for colon cancer screening. Serial spot urines in four controls demonstrated significant
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