105910
Salicylic acid
ReagentPlus®, ≥99%
Synonym(s):
2-Hydroxybenzoic acid
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All Photos(2)
About This Item
Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
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vapor density
4.8 (vs air)
Quality Level
vapor pressure
1 mmHg ( 114 °C)
product line
ReagentPlus®
Assay
≥99%
bp
211 °C (lit.)
211 °C/20 mmHg
mp
158-161 °C (lit.)
SMILES string
OC(=O)c1ccccc1O
InChI
1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChI key
YGSDEFSMJLZEOE-UHFFFAOYSA-N
Gene Information
human ... ALB(213) , PTPN1(5770)
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General description
Salicylic acid is an aromatic phenolic derivative. It can be prepared industrially via the Kolbe-Schmitt reaction. It is used as a chemical intermediate in organic synthesis for the synthesis of various organic compounds.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
314.6 °F - closed cup
Flash Point(C)
157 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
Dorothea Ellinger et al.
Plant physiology, 161(3), 1433-1444 (2013-01-22)
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been generally believed that the papillae provide a
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
Loretta Lazzarato et al.
Journal of medicinal chemistry, 51(6), 1894-1903 (2008-02-26)
A new class of products in which the phenol group of salicylic acid is linked to alkanoyl moieties bearing nitrooxy functions has been synthesized and studied for their polyvalent actions. The products were stable in acid and neutral media, while
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