Key Documents

Anti-S1PR4/EDG6 Antibody, clone 16B9.1

Name: Anti-S1PR4/EDG6 Antibody, clone 16B9.1
Brand: MM

clone 16B9.1, from mouse

Synonym(s):

Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

16B9.1, monoclonal

Application:

IHC, WB

Citations:

This product is discontinued. Contact Technical Service for assistance.

Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

16B9.1, monoclonal

species reactivity

rat, human

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgMκ

NCBI accession no.

NP_003766

UniProt accession no.

O95977

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... S1PR4(8698)

Description

General description

Sphingosine 1-phosphate receptor 4 (S1PR4), otherwise known as EDG6, is present, in varying expression levels, in the adult lymph node, bone marrow, and thymus, as well as fetal liver, lung, and thymus. It is activated by the lysosphingolipid sphingosine 1-phosphate, and is coupled to Gi and G12/13 G proteins and via their various effector molecules, SIP4 regulates cell proliferation, differentiation, motility, and migration.

~42 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human S1PR4/EDG6.

Application

Detect S1PR4/EDG6 using this Anti-S1PR4/EDG6 Antibody, clone 16B9.1 validated for use in Western Blotting & IHC.

Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected S1PR4/EDG6 in human red bone marrow and human tonsil tissues.

Physical form

Format: Purified

Analysis Note

Evaluated by Western Blot Analysis in rat spleen tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Show Differences

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This Item	SAB1306003	MABC95	SAB4500687
Sigma-Aldrich MABC97 Anti-S1PR4/EDG6 Antibody, clone 16B9.1	Sigma-Aldrich SAB1306003 ANTI-EDG6(N-TERMINAL) antibody produced in rabbit	Sigma-Aldrich MABC95 Anti-S1PR2/EDG5 Antibody, clone 6E8.1	Sigma-Aldrich SAB4500687 Anti-S1P Receptor EDG1 antibody produced in rabbit
description clone 16B9.1, from mouse	description affinity isolated antibody, buffered aqueous solution	description clone 6E8.1, from mouse	description affinity isolated antibody
species reactivity rat, human	species reactivity human, mouse	species reactivity human	species reactivity mouse, human, rat
clone 16B9.1, monoclonal	clone polyclonal	clone 6E8.1, monoclonal	clone polyclonal
biological source mouse	biological source rabbit	biological source mouse	biological source rabbit
conjugate unconjugated	conjugate -	conjugate unconjugated	conjugate unconjugated
antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody
Gene Information human ... S1PR4(8698)	Gene Information human ... S1PR4(8698)	Gene Information human ... S1PR2(9294)	Gene Information human ... S1PR1(1901)

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Storage Class

12 - Non Combustible Liquids

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Certificates of Analysis (COA)

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