MAB5550

Anti-TorsinA Antibody

ascites fluid, Chemicon^®

• Synonym(s): Anti-AMC5, Anti-DYT1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: monoclonal
• species reactivity: mouse, rat, human
• manufacturer/tradename: Chemicon^®
• technique(s): immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_000113.2
• UniProt accession no.: O14656
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... TOR1B(27348)

Description

General description

TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.

Specificity

TorsinA

Immunogen

Maltose binding protein fusion protein from human torsinA.

Application

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases

This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.

Target description

37kDa

Physical form

Ascites

Liquid. Contaings no preservative

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Positive Control: Human brain lysate, NGF treated PC12 cells.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable