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biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
rat ... Creb1(81646)
Specificity
NR3B
Immunogen
peptide corresponding to amino acids 916-930 (C-RRVRRAVVERERRVR) of mouse NR3B
Application
This Anti-NR3B Antibody is validated for use in WB for the detection of NR3B.
Quality
routinely evaluated by immunoblot on a rat brain microsomal protein preparation
Target description
98kDa
Physical form
Format: Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Keiko Matsuda et al.
Brain research. Molecular brain research, 100(1-2), 43-52 (2002-05-15)
We report the cloning and characterization of a novel NMDA receptor subunit cDNA, which encodes a predicted polypeptide of 1003 amino acids. Phylogenic analysis indicates that this new subunit is most closely related to NR3A. Therefore, we term it NR3B.
Scott E Hemby et al.
Methods in molecular biology (Clifton, N.J.), 566, 69-83 (2010-01-09)
The ability to model aspects of human addictive behaviors in laboratory animals provides an important avenue for gaining insight into the biochemical alterations associated with drug intake and the identification of targets for medication development to treat addictive disorders. The
Jon E Chatterton et al.
Nature, 415(6873), 793-798 (2002-02-02)
The N-methyl-D-aspartate subtype of glutamate receptor (NMDAR) serves critical functions in physiological and pathological processes in the central nervous system, including neuronal development, plasticity and neurodegeneration. Conventional heteromeric NMDARs composed of NR1 and NR2A-D subunits require dual agonists, glutamate and
Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration.
O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE.
Biological Psychiatry null
M Nishi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), RC185-RC185 (2001-11-22)
We have identified a novel glutamate receptor subunit on the human and mouse genome. Cloning of the mouse cDNA revealed a protein consisting of 1003 amino acids encoded by at least nine exons. This protein showed the highest similarity (51%)
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