Odd-skipped-related protein 1 (OSR1) is expressed during the beginning stages of embryogenesis in the intermediate mesoderm and in patterns during limb and branchial arch development. It has been shown that OSR1 plays a critical part in creating kidney precursor cells and regulating differentiation into kidney tubular tissue. OSR1 may play a role in limiting endoderm differentiation from mesendoderm. Expression of OSR1 is controlled by Runx2 and Ikzf1 and is key in development of embryonic, heart and urogenital tissue.
Specificity
Other homologies: Rat (96% sequence homology).
Immunogen
GST-tagged recombinant protein corresponding to human OSR1.
Application
Detect the OSR1 protein using this Anti-OSR1 validated for use in WB.
Research Category Signaling
Research Sub Category Developmental Signaling
Quality
Evaluated by Western Blot in HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected OSR1 on 10 µg of HEK293 cell lysate.
Target description
~58 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control HEK293 cell lysate
Disclaimer
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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