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Anionic Liposomes

Name: Anionic Liposomes
Brand: ALDRICH

Phosphatidylserine (PS)-based - DOPS:DOPC (2:98 molar ratio 10mM)

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About This Item

NACRES:

NA.25

UNSPSC Code:

12352211

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Properties

composition

Phosphate buffered saline

concentration

10 mM

impurities

2 mol % DOPS, 98 mol % DOPC

particle size

100 nm

pH

7.4

Description

General description

Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. One of the parameters that affects this interaction is the charge of the liposomal membrane. Phosphatidylserine (PS) is a negatviely charged molecule. The amount of the negative zeta potential in the liposomes depends on the molar percentage of the phosphatidyleserine (PS) in the formulation. The anionic-phosphatidylserine (PS) liposome catalog contains products made from 0.5 up to 100 percent DOPS with various amount of negative zeta potentials. The matrix lipid DOPC used in the formulation does not significantly contribute to the charge of the liposomes.

Application

Drug delivery
Lipid-protein interactions

Preparation Note

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Legal Information

Cellsome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

Disclaimer

For research use only

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This Item	CPS501	CPS508	CPS506
Sigma-Aldrich CPS511 Anionic Liposomes	Sigma-Aldrich CPS501 Anionic Liposomes	Sigma-Aldrich CPS508 Anionic Liposomes	Sigma-Aldrich CPS506 Anionic Liposomes
description Phosphatidylserine (PS)-based - DOPS:DOPC (2:98 molar ratio 10mM)	description Phosphatidylserine (PS)-based - DOPS:DOPC (90:10 molar ratio 10mM)	description Phosphatidylserine (PS)-based - DOPS:DOPC (20:80 molar ratio 10mM)	description Phosphatidylserine (PS)-based - DOPS:DOPC (40:60 molar ratio 10mM)
concentration 10 mM	concentration 10 mM	concentration 10 mM	concentration 10 mM
composition Phosphate buffered saline	composition Phosphate buffered saline	composition Phosphate buffered saline	composition Phosphate buffered saline
impurities 2 mol % DOPS, 98 mol % DOPC	impurities 90 mol % DOPS, 10 mol % DOPC	impurities 80 mol % DOPC, 20 mol % DOPS	impurities 40 mol % DOPS, 60 mol % DOPC
pH 7.4	pH 7.4	pH 7.4	pH 7.4
particle size 100 nm	particle size 100 nm	particle size 100 nm	particle size 100 nm

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Storage Class

12 - Non Combustible Liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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