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569313

Sigma-Aldrich

1-Bromo-3,5-dimethoxybenzene

97%

Synonym(s):

3,5-Dimethoxy-1-bromobenzene, 3,5-Dimethoxybromobenzene, 3,5-Dimethoxyphenyl bromide, 5-Bromo-1,3-dimethoxybenzene

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About This Item

Linear Formula:
BrC6H3(OCH3)2
CAS Number:
20469-65-2
Molecular Weight:
217.06
MDL number:
MFCD06200685
UNSPSC Code:
12352100
PubChem Substance ID:
24880494
NACRES:
NA.22

Assay

97%

form

solid

mp

62-66 °C (lit.)

SMILES string

COc1cc(Br)cc(OC)c1

InChI

1S/C8H9BrO2/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5H,1-2H3

InChI key

KRWRFIMBWRVMKE-UHFFFAOYSA-N

Related Categories

General description

1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.

Application

1-Bromo-3,5-dimethoxybenzene may be used to synthesize the following:
  • bis-[di-(3,5-dimethoxyphenyl)methylcyclopentadienyl]titanium(IV)dichloride,{η5 - C5H4-CH-[C6H4-(OCH3)2]2)2TiCl2 which can be used as an anti-cancer drug and is obtained via a multistep reaction process
  • 5-bromo-benzene-1,3-diol via demethylation with boron tribromide(BBr3)
  • 1-bromo-3,5-dimethoxy-2-nitrobenzene via nitration reaction

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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