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230103

Sigma-Aldrich

2,4-Diaminophenol dihydrochloride

98%

Synonym(s):

‘Amidol’

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About This Item

Linear Formula:
(H2N)2C6H3OH·2HCl
CAS Number:
137-09-7
Molecular Weight:
197.06
Beilstein:
3913728
EC Number:
205-279-4
MDL number:
MFCD00012979
UNSPSC Code:
12352100
PubChem Substance ID:
24853774
NACRES:
NA.22

Assay

98%

form

powder

mp

222 °C (dec.) (lit.)

SMILES string

Cl.Cl.Nc1ccc(O)c(N)c1

InChI

1S/C6H8N2O.2ClH/c7-4-1-2-6(9)5(8)3-4;;/h1-3,9H,7-8H2;2*1H

InChI key

KQEIJFWAXDQUPR-UHFFFAOYSA-N

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Application

2,4-Diaminophenol dihydrochloride (Amidol) was used in the dye manufacturing industries and as a color accelerator in photographic developers.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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National Toxicology Program technical report series, 401, 1-232 (1992-05-01)
2,4-Diaminophenol dihydrochloride is used in the manufacture of dyes and as a color accelerator in photographic developers. Toxicology and carcinogenesis studies were conducted by administering 2,4-diaminophenol dihydrochloride (greater than 97% pure) in corn oil by gavage to F344/N rats and
M Kh Saiatov et al.
Voprosy virusologii, 30(1), 39-43 (1985-01-01)
The method of antibody sensitization of sheep erythrocyte using amidole was employed to prepare diagnosticums for influenza A/USSR/090/77 (H1N1), A/Bangkok/1/79 (H3N2), and B/Hong Kong/75 viruses. Comparison of the potency of diagnosticums obtained on the basis of hyperimmune influenza sera and
Caroline Fribourg et al.
Biochemistry, 45(35), 10777-10785 (2006-08-31)
The light chain of activated factor IX (FIXa) is involved in a number of functional properties, including FIXa enzymatic activity. This suggests the existence of a functional link between the FIXa light chain and the catalytic domain. The FIXa structure
[Preparation of antibody erythrocyte for indicating arbovirus antigens].
T V Kiriushchenko et al.
Voprosy virusologii, (1)(1), 98-102 (1982-01-01)
V A Shamardin
Journal of hygiene, epidemiology, microbiology, and immunology, 27(3), 265-270 (1983-01-01)
Selection of the method of loading erythrocytes with preparations of immunoglobulins (IG) should be determined by the properties of the sensitins to be used. For the production of efficient antibody diagnostics it is advisable to use amidol while in the
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