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15399

Sigma-Aldrich

Boc-Lys(2-Cl-Z)-OH

≥98.0% (T)

Synonym(s):

Nα-Boc-Nε-(2-chloro-Z)-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C19H27ClN2O6
CAS Number:
Molecular Weight:
414.88
Beilstein:
3598068
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥98.0% (T)

optical activity

[α]20/D −11±1°, c = 2% in DMF

mp

70-73 °C

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1Cl)C(O)=O

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Application

Protected lysine especially suited for solid phase peptide synthesis; the 2-CI-Z protection is about 50 times more stable than the Z-group.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis.
B W Erickson et al.
Journal of the American Chemical Society, 95(11), 3757-3763 (1973-05-30)

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