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115452

Sigma-Aldrich

4-Fluoro-2-nitrobenzoic acid

≥90%

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About This Item

Linear Formula:
FC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
185.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥90%

mp

140-145 °C (lit.)

SMILES string

OC(=O)c1ccc(F)cc1[N+]([O-])=O

InChI

1S/C7H4FNO4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,(H,10,11)

InChI key

YLUCXHMYRQUERW-UHFFFAOYSA-N

Application

4-Fluoro-2-nitrobenzoic acid has been used to study the reactions of substituted pyridines with the salicyl phosphate dianion.

Biochem/physiol Actions

4-Fluoro-2-nitrobenzoic acid enhances the binding of insulin to adipocytes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Intramolecular general acid catalysis of phosphate monoester hydrolysis. The hydrolysis of salicyl phosphate.
J. Chem. Soc. Perkin Trans. II, 2, 149-155 (1972)
P E Phillips et al.
The Journal of biological chemistry, 263(23), 11175-11182 (1988-08-15)
Insulin binding to isolated rat white adipocytes at 15 degrees C, a temperature at which cellular degradation of insulin is negligible, has been found to be described by the Two-step Binding Model: R + I in equilibrium RI in equilibrium

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