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Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions.

Chemical communications (Cambridge, England) (2010-01-29)
Mohammed K Elmkaddem, Cédric Fischmeister, Christophe M Thomas, Jean-Luc Renaud
ZUSAMMENFASSUNG

A copper(i) catalyzed amination reaction utilizing aqueous ammonia and operating under mild conditions is presented. This method was employed for the efficient synthesis of various aminopyridine derivatives bearing electron withdrawing and electron donating groups.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
2-Brom-6-methoxypyridin, 97%