- A new electrochemical system for stereoselective allylic hydroxylation of cholesteryl acetate with dioxygen induced by iron picolinate complexes.
A new electrochemical system for stereoselective allylic hydroxylation of cholesteryl acetate with dioxygen induced by iron picolinate complexes.
Chemical & pharmaceutical bulletin (2004-06-10)
Iwao Okamoto, Wataru Funaki, Kyosuke Nakaya, Eiichi Kotani, Tetsuya Takeya
PMID15187401
ZUSAMMENFASSUNG
The oxygenation reaction of cholesteryl acetate 1 was examined with the Fe(III)(PA)(3)/O(2)/MeCN system using an electrochemical method. The constant potential technique gave mainly the 7-hydroxylated product stereoselectively, along with the 7-oxo product. This oxygenation system is mechanistically unique, requiring iron catalyst, dioxygen, and both cathode and anode.
MATERIALIEN