1514008

Phenacetin-Schmelzpunktstandard

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Phenacetin, 1-Acetamino-4-ethoxy-benzol, 4′-Ethoxyacetanilid, N-(4-Ethoxyphenyl)-acetamid, p-Acetophenetidid, Acetophenetidin
• Lineare Formel: CH₃CONHC₆H₄OC₂H₅
• CAS-Nummer: 62-44-2
• Molekulargewicht: 179.22
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750741
• EC Number: 200-533-0
• Beilstein/REAXYS Number: 1869238
• MDL number: MFCD00009094

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: phenacetin
• manufacturer/tradename: USP
• mp: 133-136 °C
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CCOc1ccc(NC(C)=O)cc1
• InChI: 1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
• InChI key: CPJSUEIXXCENMM-UHFFFAOYSA-N

Beschreibung

General description

Phenacetin Melting Point Standard (Phenacetin) is a lipid-soluble drug with moderate solubility with aqueous solvents. Its oral absorption is based on formulation factors like particle size. Its major metabolic route is O-dealkylation to paracetamol and its minor pathways are deacetylation and hydroxylation to form pphenetidine, 2-hydroxyphenetidine, 2- and 3-hydroxyphenacetin and N-hydroxyphenacetin.

Application

Phenacetin Melting Point Standard USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Substrat von CYP1A2 und CYP2D6

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• signalword: Danger
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pictograms: GHS02,GHS08,GHS07
• hcodes: H261,H302,H317,H341,H351
• pcodes: P202 - P231 + P232 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Muta. 2 - Skin Sens. 1 - Water-react. 2
• Lagerklasse: 4.3 - Hazardous materials which set free flammable gases upon contact with water