1357056

Leflunomid-verwandte Verbindung B

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 2-Cyan-3-hydroxy-N-(4-trifluormethylphenyl)-crotonamid
• Empirische Formel (Hill-System): C₁₂H₉F₃N₂O₂
• CAS-Nummer: 108605-62-5
• Molekulargewicht: 270.21
• MDL-Nummer: MFCD00910058
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750239
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: leflunomide
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1
• InChI: 1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
• InChIKey: UTNUDOFZCWSZMS-YFHOEESVSA-N
• Angaben zum Gen: human ... DHODH(1723)

Beschreibung

Allgemeine Beschreibung

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide is a malononitrilamide which is a water soluble metabolite of Leflunomide. It is considered as a noncompetitive inhibitor of dihydro-orotate dehydrogensae. This metabolite has been reported to initially target activated lymphocytes.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable