1138008

Clindamycinphosphat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Clindamycin-2-Phosphat, Clindamycin-2-dihydrogenphosphat
• Empirische Formel (Hill-System): C₁₈H₃₄ClN₂O₈PS
• CAS-Nummer: 24729-96-2
• Molekulargewicht: 504.96
• NACRES: NA.24
• PubChem Substance ID: 329749424
• UNSPSC Code: 41116107
• MDL number: MFCD07793328

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: clindamycin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC([C@H](C)Cl)C2O[C@H](SC)[C@H](OP(O)(O)=O)[C@@H](O)[C@H]2O
• InChI: 1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12?,13+,14-,15?,16+,18+/m0/s1
• InChI key: UFUVLHLTWXBHGZ-MWBQRTRKSA-N

Beschreibung

General description

Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.[1]

Application

Clindamycin phosphate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Clindamycin Phosphate Gel
• Clindamycin Phosphate Vaginal Cream
• Clindamycin Phosphate Topical Suspension
• Clindamycin Phosphate Vaginal Inserts
• Clindamycin Phosphate Topical Solution
• Clindamycin Injection

Biochem/physiol Actions

Wirkungsspektrum: Gram-positive Kokken und Taxoplasma. Besonders aktiv gegen anaerobe Bakterien.
Wirkmechanismus: Hemmt die Proteinsynthese in Bakterien durch Bindung der 50S ribosomalen Untereinheit

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Antibakterielles und antiprotozoales Antibiotikum der Lincosamid-Klasse.

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319,H362
• pcodes: P260 - P263 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Lact. - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable