1045009

Atropinsulfat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Atropin -sulfat (Salz) Monohydrat, α-(Hydroxymethyl)-phenylessigsäure-8-methyl-8-azabicyclo[3.2.1]oct-3-ylester, (±)-Tropintropat
• Lineare Formel: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• CAS-Nummer: 5908-99-6
• Molekulargewicht: 694.83
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749082
• MDL number: MFCD00074815
• Beilstein/REAXYS Number: 6109275

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: atropine
• manufacturer/tradename: USP
• mp: 189-192 °C (A) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• InChI key: JPKKQJKQTPNWTR-CHYDPLAESA-N
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Atropine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Atropine Sulfate Injection
• Atropine Sulfate Ophthalmic Solution
• Atropine Sulfate Ophthalmic Ointment
• Diphenoxylate Hydrochloride and Atropine Sulfate Tablets
• Diphenoxylate Hydrochloride and Atropine Sulfate Oral Solution
• Atropine

Biochem/physiol Actions

Kompetitiver nichtselektiver Antagonist an zentralen und peripheren muskarinischen Acetylcholinrezeptoren.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H330
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• pcodes: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233