T6443

Tyrphostin AG 370

≥98%

• Synonym(e): 2-Amino-4-(1H-indo-5′-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7
• Empirische Formel (Hill-System): C₁₅H₉N₅
• CAS-Nummer: 134036-53-6
• Molekulargewicht: 259.27
• UNSPSC Code: 12352200
• PubChem Substance ID: 329826844
• MDL number: MFCD00236449

Eigenschaften

• assay: ≥98%
• form: solid
• mp: 289 °C
• solubility: DMSO: soluble
• storage temp.: −20°C
• SMILES string: NC(\C(=C/c1ccc2[nH]ccc2c1)C#N)=C(\C#N)C#N
• InChI: 1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2/b12-6-
• InChI key: CMMDWEJTQUTCKG-SDQBBNPISA-N

Beschreibung

Application

Tyrphostin AG 370 has been used for inhibiting platelet-derived growth factor (PDGF) signaling in human mesenchymal stem cells^1,2.

Biochem/physiol Actions

Inhibitor of PDGF-induced cell proliferation.

Preparation Note

Tyrphostin AG 370 is soluble in DMSO.

Disclaimer

Photosensitive

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)