T6134

Tylosin

potency: ≥800 units/mg tylosin

• Synonym(e): [R-(R′R′)]-2,3-Dihydroxybutanedionate Tylosin salt
• NACRES: NA.85
• PubChem Substance ID: 24900350
• UNSPSC Code: 51283225
• MDL number: MFCD07783824

Eigenschaften

• form: powder
• Quality Segment: 200
• potency: ≥800 units/mg tylosin
• storage condition: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• color: off-white to yellow
• solubility: H₂O: soluble 50 mg/mL
• antibiotic activity spectrum: Gram-positive bacteria, mycoplasma
• mode of action: protein synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
• InChI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
• InChI key: ICVKYYINQHWDLM-KBEWXLTPSA-N

Beschreibung

General description

Chemical structure: macrolide

Application

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticum and Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.

Biochem/physiol Actions

Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

Other Notes

Mischung aus Tylosin A, B, C, und D -tartrat.

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Disclaimer

Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H317,H334
• pcodes: P280 - P302 + P352
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves