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Merck

T3001

Sigma-Aldrich

(+)-α-Tocopherol acetate

oil or semi-solid, ~1360 IU/g

Synonym(e):

Vitamin E acetate

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About This Item

Empirische Formel (Hill-System):
C31H52O3
CAS-Nummer:
Molekulargewicht:
472.74
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
eCl@ss:
34058007
PubChem Substanz-ID:
NACRES:
NA.79

Biologische Quelle

plant

Qualitätsniveau

Beschreibung

Synthesized from natural α-tocopherol

Form

oil or semi-solid

Spezifische Aktivität

~1360 IU/g

Farbe

yellow

mp (Schmelzpunkt)

~25 °C (lit.)

Lagertemp.

room temp

SMILES String

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChIKey

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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Allgemeine Beschreibung

α-Tocopherol acetate is a fat soluble vitamin and a form of vitamin E. It can be obtained through dietary sources. RRRα-Tocopherol is a natural form of α-tocopherol.

Anwendung

(+)-α-Tocopherol acetate has been used:
  • as a component of growth medium for retinal cell lines
  • as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
  • in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Biochem./physiol. Wirkung

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.
Tocopherols (TCP) (vitamin E) are a series (α, β,γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Vorsicht

Does not air oxidize.

H-Sätze

P-Sätze

Gefahreneinstufungen

Aquatic Chronic 4

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Persönliche Schutzausrüstung

Eyeshields, Gloves


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Die Dokumentenbibliothek aufrufen

Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials
Bolognesi C, et al.
EFSA Journal, 14(3), 4412-4412 (2016)
Resveratrol liposomes and lipid nanocarriers: comparison of characteristics and inducing browning of white adipocytes
Zu Y, et al.
Colloids and Surfaces. B, Biointerfaces, 164, 414-423 (2018)
Effects of natural (RRR α-tocopherol acetate) or synthetic (all-rac α-tocopherol acetate) vitamin E supplementation on reproductive efficiency in beef cows.
Horn M, Gunn P, Van Emon M, et al.
Journal of Animal Science, 88, 3121-3127 (2011)
Partial nutrient characterization of arugula (rocket-Eruca sativa L.) and the effect of heat treatment on its lipoxidase activity
Tassi EMM, et al.
Brazilian Journal of Food Technology, 21 (2018)
Ye Zhang et al.
The journal of physical chemistry. A, 115(29), 8242-8247 (2011-06-17)
Photoionization is known to take place when α-tocopherol (TOH) is excited to the S(1) state in a polar medium. It has been previously suggested that TO(•) is formed only as a result of proton release by TOH(•+), a process that

Artikel

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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