T3001

(+)-α-Tocopherol acetate

oil or semi-solid, ~1360 IU/g

• Synonym(e): Vitamin E acetate
• Empirische Formel (Hill-System): C₃₁H₅₂O₃
• CAS-Nummer: 58-95-7
• Molekulargewicht: 472.74
• PubChem Substance ID: 24900095
• eCl@ss: 34058007
• UNSPSC Code: 12352205
• NACRES: NA.79
• EC Number: 200-405-4
• MDL number: MFCD00072052

Eigenschaften

• biological source: plant
• Quality Segment: 200
• description: Synthesized from natural α-tocopherol
• form: oil or semi-solid
• specific activity: ~1360 IU/g
• color: yellow
• mp: ~25 °C (lit.)
• storage temp.: room temp
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
• InChI: 1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
• InChI key: ZAKOWWREFLAJOT-CEFNRUSXSA-N

Beschreibung

General description

α-Tocopherol acetate is a fat soluble vitamin and a form of vitamin E. It can be obtained through dietary sources. RRRα-Tocopherol is a natural form of α-tocopherol.

Application

(+)-α-Tocopherol acetate has been used:

• as a component of growth medium for retinal cell lines
• as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
• in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Biochem/physiol Actions

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.

Tocopherols (TCP) (vitamin E) are a series (α, β,γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Disclaimer

Does not air oxidize.

Sicherheitshinweise

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• ppe: Eyeshields, Gloves