T0953

14-3-3 Tau/Theta histidine-tagged human

recombinant, expressed in E. coli, C-terminal, ≥90% (SDS-PAGE), buffered aqueous glycerol solution

• Synonym(e): 14-3-3 tau, 14-3-3 theta, 14-3-3t, 1C5, Bap1, HS1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, YWHAQ
• UNSPSC Code: 12352202
• Assay: ≥90% (SDS-PAGE)
• Form: buffered aqueous glycerol solution

Eigenschaften

• recombinant: expressed in E. coli
• Quality Segment: 200
• assay: ≥90% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• mol wt: ~30 kDa (14-3-3 proteins)
• UniProt accession no.: P27348
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... YWHAQ(10971)

Beschreibung

Biochem/physiol Actions

14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control.[1][2] Co-immunoprecipitation experiments demonstrate the interaction of 14-3-3 τ/θ adaptor protein with various proteins (UCP3, PKCζ).[3] 14-3-3 τ/θ is involved in cell cycle arrest and cellular differentiation. 14-3-3 τ/θ plays an active role in mediating Vpr-induced cell cycle arrest in human T cells.[4]

Physical form

Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)