SRP6090

AKR1B10 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): AKR1B11, ALDRLn, ARL-1, Aldo-keto reductase family member B10, HIS
• NACRES: NA.32
• UNSPSC Code: 12352204
• Biological source: human
• Recombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Mol wt: 36 kDa

Eigenschaften

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: 36 kDa
• packaging: pkg of 100 μg
• NCBI accession no.: O60218
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... AKR1B10(57016)

Beschreibung

General description

AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications. It has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer.

Physical form

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFDAEY

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable