SRP4869

Placental Lactogen human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Synonym(e): CSA, CSH1, CSH2, CSMT, FLJ75407, PL
• UNSPSC Code: 51111800
• NACRES: NA.32
• MDL number: MFCD00131483
• Form: lyophilized
• Assay: ≥95% (HPLC), ≥95% (SDS-PAGE)
• Biological source: human
• Recombinant: expressed in E. coli
• Mol wt: ~22.3 kDa

Eigenschaften

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥95% (HPLC), ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: ~22.3 kDa
• packaging: pkg of 20 μg
• storage condition: avoid repeated freeze/thaw cycles
• technique(s): cell based assay: suitable
• impurities: endotoxin, tested
• NCBI accession no.: P01243
• UniProt accession no.: Q6PF11
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... CSH1(1442)

Beschreibung

General description

Human placental lactogen (HPL), also called human chorionic somatomammotropin 1, is a polypeptide placental hormone. Its structure and function is similar to that of growth hormone. The gene encoding this protein is localized on human chromosome 17. Recombinant human placental lactogen is a 22.3kDa protein.

Biochem/physiol Actions

Human placental lactogen (HPL) modifies the metabolic state of the mother during pregnancy to facilitate the energy supply, glucose supply and growth of the fetus. Studies show that targeted expression of this protein in transgenic mice lead to an increase in proliferation of β-cells.

Physical form

Sterile filtered and lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.