SML3494

β-Benzamide adenine dinucleotide sodium salt

≥95% (HPLC), IMPDH inhibitor, powder

• Synonym(e): Adenosine 5′-(trihydrogen diphosphate) P′→5′-ester with 3-β-D-ribofuranosylbenzamide sodium salt, BAD, benzamide adenine dinucleotide sodium salt
• Empirische Formel (Hill-System): C₂₂H₂₆N₆O₁₄P₂Na₂
• Molekulargewicht: 706.40
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Produktname: β-Benzamide adenine dinucleotide sodium salt, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• storage temp.: -10 to -25°C
• SMILES string: O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N(C=N3)C4=C3C(N)=NC=N4)O2)(O[Na])=O)(O[Na])=O)O[C@H]1C5=CC(C(N)=O)=CC=C5

Beschreibung

Biochem/physiol Actions

β-Benzamide adenine dinucleotide (BAD), an analogue of nicotinamide adenine dinucleotide (β-NAD+), is an active metabolite of benzamide riboside and a potent inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH). Also, β-Benzamide adenine dinucleotide is a non-hydrolysable substrate/inhibitor of NADases and PARP enzymes. A higher concentration (Ki = 90 μM) it inhibits human NAD kinase.

Analogue of nicotinamide adenine dinucleotide (β-NAD+); inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids