SML2966

Z-RLRGG-AMC Acetate

≥95% (HPLC)

• Synonym(e): N2-[(Phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-glycinamide, Z-Arg-Leu-Arg-Gly-Gly-7-amido-4-methylcoumarin, Z-Arg-Leu-Arg-Gly-Gly-AMC
• Empirische Formel (Hill-System): C₄₀H₅₆N₁₂O₉ · xC₂H₄O₂
• CAS-Nummer: 167698-69-3
• Molekulargewicht: 848.95 (free base basis)
• UNSPSC Code: 12352209
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: film or powder

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: film or powder
• color: white to beige
• storage temp.: −20°C
• SMILES string: FC(F)(F)C(=O)O.N([C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)NCC(=O)Nc2cc3c(cc2)C(=CC(=O)O3)C)C(=O)OCc1ccccc1
• InChI: 1S/C40H56N12O9.C2HF3O2/c1-23(2)17-30(51-36(57)29(12-8-16-46-39(43)44)52-40(59)60-22-25-9-5-4-6-10-25)37(58)50-28(11-7-15-45-38(41)42)35(56)48-20-32(53)47-21-33(54)49-26-13-14-27-24(3)18-34(55)61-31(27)19-26;3-2(4,5)1(6)7/h4-6,9-10,13-14,18-19,23,28-30H,7-
• InChI key: CMGDVBCGNGERLC-SZOHVZSOSA-N

Beschreibung

Biochem/physiol Actions

Z-RLRGG-AMC is a fluorogenic substrate for the MERS-CoV, SARS-CoV, SARS-CoV-2 papain-like protease (PLpros), deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases, which consists of the Ub and ISG15 C-terminal sequences. Z-RLRGG-AMC excitation wavelength is 340 nm, and emission wavelength is 460 nm.

fluorogenic substrate for the MERS-CoV, SARS-CoV, SARS-CoV-2 papain-like protease (PLpros), deubiquitinating enzyme isopeptidase T (IPaseT)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable