SML2727

BAY 41-8543

≥98% (HPLC)

• Synonym(e): 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine, BAY41-8543
• Empirische Formel (Hill-System): C₂₁H₂₁FN₈O
• CAS-Nummer: 256498-66-5
• Molekulargewicht: 420.44
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD18382081
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to very dark brown
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: Fc1c(cccc1)C[n]2nc(c5c2nccc5)c3nc(c(c(n3)N)N4CCOCC4)N
• InChI: 1S/C21H21FN8O/c22-15-6-2-1-4-13(15)12-30-21-14(5-3-7-25-21)16(28-30)20-26-18(23)17(19(24)27-20)29-8-10-31-11-9-29/h1-7H,8-12H2,(H4,23,24,26,27)
• InChI key: AQYFUZRYBJBAGZ-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

BAY 41-8543 is a stimulator of soluble Guanylyl cyclase (guanylate cyclase, sGC), the primary cellular receptor for nitric oxide (NO).

Guanylyl cyclase (sGC) stimulator

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable