SML2365

Phenprocoumon

≥97% (HPLC)

• Synonym(e): 2-Hydroxy-3-(1-phenylpropyl)-4H-1-benzopyran-4-one, 4-Hydroxy-3-(1-phenylpropyl)-2H-1-Benzopyran-2-one
• Empirische Formel (Hill-System): C₁₈H₁₆O₃
• CAS-Nummer: 435-97-2
• Molekulargewicht: 280.32
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00865273
• Assay: ≥97% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C18H16O3/c1-2-13(12-8-4-3-5-9-12)16-17(19)14-10-6-7-11-15(14)21-18(16)20/h3-11,13,20H,2H2,1H3
• InChI key: QNDUUBVQYBBRBW-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant

Phenprocoumon is a coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant. It was recently found to act synergistically with flutamide to modulate the stability of the androgen receptor (AR) and resensitize AR-mutant prostate cancer cells to flutamide.

Sicherheitshinweise

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H361d,H373
• pcodes: P201 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2 - STOT RE 2
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable