SML2142

Silodosin

≥98% (HPLC), alpha 1-adrenoceptor antagonist, powder

• Synonym(e): 1-(3-Hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2­trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide, Rapaflo, Rapallo, Silodyx, Urief
• Empirische Formel (Hill-System): C₂₅H₃₂F₃N₃O₄
• CAS-Nummer: 160970-54-7
• Molekulargewicht: 495.53
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00930170
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Silodosin, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: NC(C1=CC(C[C@@H](C)NCCOC2=C(OCC(F)(F)F)C=CC=C2)=CC3=C1N(CCCO)CC3)=O
• InChI: 1S/C25H32F3N3O4/c1-17(30-8-12-34-21-5-2-3-6-22(21)35-16-25(26,27)28)13-18-14-19-7-10-31(9-4-11-32)23(19)20(15-18)24(29)33/h2-3,5-6,14-15,17,30,32H,4,7-13,16H2,1H3,(H2,29,33)/t17-/m1/s1
• InChI key: PNCPYILNMDWPEY-QGZVFWFLSA-N

Beschreibung

Biochem/physiol Actions

Selective alpha 1-adrenoceptor antagonist

Silodosin is a selective alpha 1-adrenoceptor antagonist with high affinity for the ?1A adrenergic receptor, used clinically for the treatment of benign prostatic hyperplasia (BPH).

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H373
• pcodes: P301 + P312 + P330 - P314
• Hazard Classifications: Acute Tox. 4 Oral - STOT RE 2
• target_organs: Liver
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable