SML1544

VPC-14228

≥98% (HPLC)

• Synonym(e): 2-Morpholino-4-phenylthiazole, 4-(4-Phenyl-2-thiazolyl)-morpholine, 4-(4-Phenylthiazol-2-yl)morpholine
• Empirische Formel (Hill-System): C₁₃H₁₄N₂OS
• CAS-Nummer: 19983-28-9
• Molekulargewicht: 246.33
• NACRES: NA.77
• PubChem Substance ID: 329825954
• UNSPSC Code: 51111800
• MDL number: MFCD00628805
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: C1(N2CCOCC2)=NC(C3=CC=CC=C3)=CS1
• InChI: 1S/C13H14N2OS/c1-2-4-11(5-3-1)12-10-17-13(14-12)15-6-8-16-9-7-15/h1-5,10H,6-9H2
• InChI key: MRNNJVNMXOZEQC-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants.

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR).

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable