SML1284

Efavirenz Ready Made Solution

10 mg/mL in DMSO

• Synonym(e): (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one, (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
• Empirische Formel (Hill-System): C₁₄H₉ClF₃NO₂
• CAS-Nummer: 154598-52-4
• Molekulargewicht: 315.67
• UNSPSC Code: 12352200
• NACRES: NA.77
• Form: DMSO solution

Eigenschaften

• form: DMSO solution
• Quality Segment: 200
• concentration: 10 mg/mL in DMSO
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: FC(F)(F)[C@]2(OC(=O)Nc3c2cc(cc3)Cl)C#CC1CC1
• InChI: 1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
• InChI key: XPOQHMRABVBWPR-ZDUSSCGKSA-N

Beschreibung

Biochem/physiol Actions

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI).

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). Efavirenz is an anti-HIV drug, commonly used in combination therapy for AIDs treatment. Efavirenz is part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.

The plasma levels of this drug can determine the failure of treatment and CNS (central nervous system) side-effects in patients infected with HIV (human immunodeficiency virus). [1]

Sicherheitshinweise

• pictograms: GHS08,GHS09
• signalword: Danger
• hcodes: H360,H411
• pcodes: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Chronic 2 - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: 188.6 °F
• flash_point_c: 87 °C