SML0154

SPV-106

≥98% (HPLC)

• Synonym(e): 2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b
• Empirische Formel (Hill-System): C₂₂H₄₀O₄
• CAS-Nummer: 1036939-38-4
• Molekulargewicht: 368.55
• NACRES: NA.77
• PubChem Substance ID: 329825202
• UNSPSC Code: 12352200
• MDL number: MFCD20527327
• Assay: ≥98% (HPLC)
• Form: oil

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: oil
• color: colorless
• storage temp.: 2-8°C
• SMILES string: CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC
• InChI: 1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3
• InChI key: APIJHPAXMCKJBY-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Mixed histone acetylase inhibitor/activator

SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable