S1195

ST638

≥98% (HPLC), solid

• Synonym(e): α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide
• Empirische Formel (Hill-System): C₁₉H₁₈N₂O₃S
• CAS-Nummer: 107761-24-0
• Molekulargewicht: 354.42
• NACRES: NA.77
• PubChem Substance ID: 329824465
• UNSPSC Code: 12352200
• MDL number: MFCD00236446
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• color: yellow
• mp: 134-135.5 °C
• solubility: DMSO: 19 mg/mL
• storage temp.: −20°C
• SMILES string: CCOc1cc(cc(CSc2ccccc2)c1O)\C=C(/C#N)C(N)=O
• InChI: 1S/C19H18N2O3S/c1-2-24-17-10-13(8-14(11-20)19(21)23)9-15(18(17)22)12-25-16-6-4-3-5-7-16/h3-10,22H,2,12H2,1H3,(H2,21,23)/b14-8+
• InChI key: YKLMGKWXBLSKPK-RIYZIHGNSA-N

Beschreibung

Biochem/physiol Actions

Protein tyrosine kinase inhibitor (IC₅₀ = 370 nM). Also inhibits HGF-induced MAP kinase activation in hepatocytes and inhibits phospholipase D activity in human neutrophils.

Packaging

Light sensitive and packaged under nitrogen.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)