RAB0283

Human IL-1ra ELISA Kit

for serum, plasma, cell culture supernatant and urine

• NACRES: NA.84
• UNSPSC Code: 41116158
• Gene information: human ... IL1RN(3557)
• Input: sample type serum; sample type cell culture supernatant(s); sample type plasma; sample type urine
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Eigenschaften

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type serum; sample type cell culture supernatant(s); sample type plasma; sample type urine
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 100 pg/mL; standard curve range: 0.124-30 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL1RN(3557)

Beschreibung

General description

The Human IL-1ra ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-1ra in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-1 Receptor Antagonist

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α and IL-1β by competitively binding to their type I and type II receptors. IL-1RA plays a vital role in inhibition of acute pro-inflammatory response and forbidding chronic inflammation from damaging healthy tissues. Abnormal expression of IL-1RA leads to development of inflammatory or autoimmune related diseases.[1] Allelic polymorphism of IL-1RA leads to inflammatory bowel disease (IBD).[2] Therapeutically, IL-1RA may help in the treatment of sepsis, rheumatoid arthritis, asthma.[3][4][5] Overexpression of IL-1RA is observed in serum of psoriatic arthritis (PsA) patients.[6]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

Sicherheitshinweise

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Lagerklasse: 10 - Combustible liquids