R6775

Anti-Retinoblastoma antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(e): Anti-Rb
• UNSPSC Code: 12352203
• MDL number: MFCD00282455

Eigenschaften

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 105 kDa
• species reactivity: human
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:5,000 using human colon adenocarcinoma tissue, microarray: suitable, western blot: 1:100 using human acute lymphoma Jurkat cell lysate
• UniProt accession no.: P06400
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... RB1(5925)

Beschreibung

Immunogen

synthetic peptide corresponding to amino acids 914-928 of the C-terminal region of human p105 retinoblastoma protein (p105 Rb) with N-terminally added cysteine, conjugated to maleimide-activated KLH.

Biochem/physiol Actions

This sequence recognized by the antibody is highly conserved across species (e.g., mouse, rat p105 Rb) and is not found in p107 Rb and p130 Rb.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.