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Merck

R4632

Sigma-Aldrich

Retinylacetat

synthetic, crystalline solid or supercooled liquid

Synonym(e):

Retinolacetat, Vitamin A-acetat

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About This Item

Empirische Formel (Hill-System):
C22H32O2
CAS-Nummer:
Molekulargewicht:
328.49
Beilstein:
1915439
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
eCl@ss:
34058009
PubChem Substanz-ID:
NACRES:
NA.79
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Biologische Quelle

synthetic

Assay

≥90% (HPLC)

Form

crystalline solid or supercooled liquid

Wirksamkeit

2,600,000-2,940,000 I.U. per g

Farbe

light yellow to dark yellow

mp (Schmelzpunkt)

57-58 °C
~58 °C (lit.)

Lagertemp.

−20°C

SMILES String

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChIKey

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Allgemeine Beschreibung

Vitamin A usually occurs in food as retinyl esters,[1] which are the pre-formed sources of vitamin A.[2] Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils.[3]

Anwendung

Retinyl acetate has been used:
  • to study its effects on cochlear development in mice[4]
  • as a component of an internal standard to quantify antioxidants in yolk[4]
  • as an internal standard to determine serum retinol concentration[5]

Biochem./physiol. Wirkung

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.

Physikalische Form

Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid

Hinweis zur Analyse

Activity based on HPLC comparison to USP standard.

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Aquatic Chronic 4 - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Kunden haben sich ebenfalls angesehen

The common marmoset in captivity and biomedical research
Marini RP
Common Fragrance and Flavor Materials (2018)
Capillary electrophoresis Food Additives
Frazier RA
Encyclopedia of Separation Science (2007)
Assessment of the relative dose-response test based on serum retinol-binding protein instead of serum retinol in determining low hepatic vitamin A stores
Fujita M, et al.
American Journal of Clinical Nutrition (2009)
Effects of retinoid treatment on cochlear development, connexin expression and hearing thresholds in mice
Kim Yy, et al.
Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-rhino-laryngologie et de Chirurgie Cervico-Faciale (2018)
Buhler Volker
Vademecum for Vitamin Formulations (2001)

Protokolle

GB method with Ascentis® Express C30 column achieves baseline resolution for Vitamin A and E critical pair.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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