R0281

RNF11 human

recombinant, expressed in E. coli (histidine-tagged), ≥90% (SDS-PAGE), buffered aqueous solution

• Synonym(e): CGI-123, MGC51169, RING Finger Protein 11, SID1669
• UNSPSC Code: 12352200

Eigenschaften

• recombinant: expressed in E. coli (histidine-tagged)
• assay: ≥90% (SDS-PAGE)
• form: buffered aqueous solution
• UniProt accession no.: Q9Y3C5
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... RNF11(26994)

Beschreibung

Biochem/physiol Actions

RNF11 (RING Finger Protein 11) is a RING E3 ubiquitin ligase with potential to mediate ubiquitination and subsequent proteolysis. RNF11 binds numerous proteins in a variety of cellular pathways, including TGFβ and EGFR signaling. RNF11 expression is elevated in breast and prostate cancer. RNF11 may represent an important target for novel cancer therapies.

Physical form

Solution in 50 mM Tris, pH 7.5, 150 mM NaCl, 1 mM DTT, and 30% glycerol (w/v).

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• Was ist los?: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)