Q1250

Chinin -hemisulfat (Salz) Monohydrat

synthetic, ≥90% (HPLC), Potassium channel blocker

• Synonym(e): Chinin-sulfat (2:1) (Salz) Dihydrat
• Empirische Formel (Hill-System): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS-Nummer: 207671-44-1
• Molekulargewicht: 391.47
• NACRES: NA.77
• PubChem Substance ID: 57654578
• UNSPSC Code: 12352210
• MDL number: MFCD00150790
• Beilstein/REAXYS Number: 6113937
• Assay: ≥90% (HPLC)

Eigenschaften

• Produktname: Chinin -hemisulfat (Salz) Monohydrat, synthetic, ≥90% (HPLC)
• biological source: synthetic
• Quality Segment: 200
• assay: ≥90% (HPLC)
• mp: ~225 °C (dec.) (lit.)
• solubility: H₂O: slightly soluble 1.2 mg/mL, ethanol: 8 mg/mL
• antibiotic activity spectrum: parasites
• mode of action: enzyme | inhibits
• originator: Bayer
• SMILES string: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI key: ZHNFLHYOFXQIOW-LPYZJUEESA-N

Beschreibung

Application

Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.

Biochem/physiol Actions

Quinine has analgesic property.

blockiert Kaliumkanäle. Anti-Malaria

blockiert Kaliumkanäle. Anti-Malaria, anticholinerges, antihypertensives und hypoglykemisches Agens; ursprünglich aus südafrikanischen Bäumen der Gattung Cinchona isoliert.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves