PHG0007

MOPS

• Synonym(e): 3-Morpholino-propansulfonsäure, 4-Morpholin-propansulfonsäure
• Empirische Formel (Hill-System): C₇H₁₅NO₄S
• CAS-Nummer: 1132-61-2
• Molekulargewicht: 209.26
• EC Number: 214-478-5
• UNSPSC Code: 12161700
• NACRES: NA.21
• Beilstein/REAXYS Number: 1106776
• MDL number: MFCD00006183

Eigenschaften

• biological source: synthetic
• assay: ≥99.5%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin, microbial, and trace metals; tested
• pH: 2.5-4 (1 M in H₂O)
• useful pH range: 6.5-7.9
• pKa (25 °C): 7.2
• λ: 1 M in H₂O
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: OS(=O)(=O)CCCN1CCOCC1
• InChI: 1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
• InChI key: DVLFYONBTKHTER-UHFFFAOYSA-N

Beschreibung

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup