P4236

Cyclic Pifithrin-α hydrobromide

≥98% (HPLC)

• Synonym(e): 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide, Cyclic PFT-α hydrobromide, Pifithrin-α, cyclic, QB102
• Empirische Formel (Hill-System): C₁₆H₁₆N₂S · HBr
• CAS-Nummer: 511296-88-1
• Molekulargewicht: 349.29
• NACRES: NA.77
• PubChem Substance ID: 24898515
• UNSPSC Code: 12352200
• MDL number: MFCD02683960
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• solubility: DMSO: 20 mg/mL
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: Br[H].Cc1ccc(cc1)-c2cn3c4CCCCc4sc3n2
• InChI: 1S/C16H16N2S.BrH/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;/h6-10H,2-5H2,1H3;1H
• InChI key: SGNCOAOESGSEOP-UHFFFAOYSA-N

Beschreibung

Application

Cyclic Pifithrin-α hydrobromide has been used as p53 inhibitor to study its role in cigarette smoke−induced apoptosis of pulmonary endothelial cells.

Biochem/physiol Actions

A stable analog of Pifithrin-α (Product Code P4359) with similar biological activities and lower cellular toxicity.

Packaging

Protect from light.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)