Direkt zum Inhalt
Merck

P3591

Sigma-Aldrich

1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt

≥99%

Synonym(e):

L-α-Phosphatidic acid, dioctanoyl sodium salt

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Lineare Formel:
C19H36O8PNa
CAS-Nummer:
Molekulargewicht:
446.45
MDL-Nummer:
UNSPSC-Code:
12352202
NACRES:
NA.77

Assay

≥99%

Form

powder

Lagertemp.

−20°C

InChI

1S/C19H37O8P.Na/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2;/h17H,3-16H2,1-2H3,(H2,22,23,24);/q;+1/p-1/t17-;/m1./s1

InChIKey

ZNDNSOYDPUTHKQ-UNTBIKODSA-M

Allgemeine Beschreibung

1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt is a cell-permeable phosphatidic acid (PA).

Anwendung

1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt has been used:
  • to study its effects on neural stem/precursor cell (NSC) proliferation
  • to study the effects of phosphatidic acid (PA) on actin filament dynamics in Arabidopsis thaliana epidermal leaf cells
  • to treat vector-transfected cells and to verify the attenuation of hypoxia-inducible factor-1α (HIF-1α) induction in phospholipase D (PLD)-transfected cells by butanol

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Jindřiška Matoušková et al.
Plant science : an international journal of experimental plant biology, 223, 36-44 (2014-04-29)
Changes in actin cytoskeleton dynamics are one of the crucial players in many physiological as well as non-physiological processes in plant cells. Positioning of actin filament arrays is necessary for successful establishment of primary lines of defense toward pathogen attack
Yuko Fujita et al.
Biochemical and biophysical research communications, 370(1), 169-173 (2008-03-25)
While a mother's excessive alcohol consumption during pregnancy is known to have adverse effects on fetal neural development, little is known about the underlying mechanism of these effects. In order to investigate these mechanisms, we investigated the toxic effect of
ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling
Fujita Y, et al.
Biochemical and Biophysical Research Communications, 370(1), 169-173 (2008)
Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
Han S, et al.
Experimental & Molecular Medicine, 46(12), e126-e126 (2014)
Songyi Han et al.
Experimental & molecular medicine, 46, e126-e126 (2014-12-20)
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is believed to play an important role in tumorigenesis. In this

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.