Osteocalcin, Human, product number O5761 is carboxylated.
Post-translational modification by a vitamin K dependent carboxylase produces three g-carboxyglutamic acid residues at positions 17, 21 and 24. The mature protein contains 49 amino acids and a single intrachain disulfide bond joining Cys23 to Cys29.
Fortfahren mit
O5761
Osteocalcin fragment 1-49 Human
≥94% (HPLC), solid
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
Ansicht ändern
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
500 μg | Warenkorb auf Verfügbarkeit prüfen | € 797,00 |
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.580,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C269H381N67O82S2
CAS-Nummer:
Molekulargewicht:
5929.43
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenQuality Segment
assay
≥94% (HPLC)
form
solid
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... BGLAP(632)
General description
Bone γ-carboxyglutamate protein (BGLAP) or osteocalcin (OCN) is a non-collagenous bone matrix protein expressed by osteoblasts. It possesses a Gla (γ carboxyglutamate) domain. The gene encoding OCN is localized on human chromosome 1q22.
Calcium-binding protein found in dentin and possibly other mineralized tissues.
Application
Human osteocalcin fragment 1-49 has been used for the identification and characterization of glycation adducts on osteocalcin. It has also been used to study its effects on the differentiation of mouse myoblast cell line C2C12.
Biochem/physiol Actions
Bone γ-carboxyglutamate protein (BGLAP) regulates osteogenic differentiation of mesenchymal stromal cells. It has a role in bone turnover and mineralization. The protein also has a role in energy metabolism. BGLAP may act as a mediator between glucose metabolism and bone tissue.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| assay ≥94% (HPLC) | assay ≥97% (HPLC) | assay - | assay ≥95% (SDS-PAGE) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form solid | form powder | form - | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. −20°C |
| Gene Information human ... BGLAP(632) | Gene Information human ... CALCA(796) | Gene Information human ... BGLAP(632) | Gene Information human ... SPP1(6696) |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
-
Hi, Is there any information regarding the gamma carboxylation status of this product?
1 answer-
Helpful?
-