O1141

Olanzapin

≥98% (HPLC), 5-HT2 serotonin and D1/D2 dopamine receptor antagonist, powder

• Synonym(e): 2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepin
• Empirische Formel (Hill-System): C₁₇H₂₀N₄S
• CAS-Nummer: 132539-06-1
• Molekulargewicht: 312.43
• NACRES: NA.77
• PubChem Substance ID: 329818894
• UNSPSC Code: 12352200
• MDL number: MFCD00866702
• Beilstein/REAXYS Number: 7655141
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Olanzapin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: DMSO: >15 mg/mL
• originator: Eli Lilly
• storage temp.: 2-8°C
• SMILES string: CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24
• InChI: 1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
• InChI key: KVWDHTXUZHCGIO-UHFFFAOYSA-N
• Gene Information: human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356), HTR2C(3358)

Beschreibung

Biochem/physiol Actions

Olanzapine is a 5-HT2 serotonin and D1/D2 dopamine receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H317,H336
• pcodes: P261 - P264 - P271 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Central nervous system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3